Here's what I could find in the help
When your mouse has a scroll wheel, it should work with Vim in the GUI. How
it works depends on your system. It might also work in an xterm
|xterm-mouse-wheel|. By default only vertical scroll wheels are supported,
but some GUIs also support horizontal scroll wheels.
and
For the X11 GUIs (Motif, Athena and GTK) scrolling the wheel generates key
presses <ScrollWheelUp>, <ScrollWheelDown>, <ScrollWheelLeft> and
<ScrollWheelRight>. For example, if you push the scroll wheel upwards a
<ScrollWheelUp> key press is generated causing the window to scroll upwards
(while the text is actually moving downwards). The default action for these
keys are:
<ScrollWheelUp> scroll three lines up *<ScrollWheelUp>*
<S-ScrollWheelUp> scroll one page up *<S-ScrollWheelUp>*
<C-ScrollWheelUp> scroll one page up *<C-ScrollWheelUp>*
<ScrollWheelDown> scroll three lines down *<ScrollWheelDown>*
<S-ScrollWheelDown> scroll one page down *<S-ScrollWheelDown>*
<C-ScrollWheelDown> scroll one page down *<C-ScrollWheelDown>*
<ScrollWheelLeft> scroll six columns left *<ScrollWheelLeft>*
<S-ScrollWheelLeft> scroll one page left *<S-ScrollWheelLeft>*
<C-ScrollWheelLeft> scroll one page left *<C-ScrollWheelLeft>*
<ScrollWheelRight> scroll six columns right *<ScrollWheelRight>*
<S-ScrollWheelRight> scroll one page right *<S-ScrollWheelRight>*
<C-ScrollWheelRight> scroll one page right *<C-ScrollWheelRight>*
This should work in all modes, except when editing the command line.
and finally
Note that horizontal scrolling only works if 'nowrap' is set. Also, unless
the "h" flag in 'guioptions' is set, the cursor moves to the longest visible
line if the cursor line is about to be scrolled off the screen (similarly to
how the horizontal scrollbar works).
So it may have something to do with How it works depends on your system
—the listed systems are mostly X11. I don't have a MacVim to check more relevant docs on though:
:help mac
NOTE: This file is a bit outdated. You might find more useful info here:
http://macvim.org/
Some more things I’ve learned—MacVim tries to scroll the window, rather than scrolling the cursor. This seems to be acceptable and even considered default behavior (though I agree it’s different from the terminal). Still looking for a solution, but I suspect it will require changing the way the mouse works with the gui.